As of v8.0, the Keyboard Maestro editor is fully OSA (Open Scripting Architecture) compatible. This means you can edit your Keyboard Maestro macros from AppleScript in a variety of powerful ways.

The Keyboard Maestro Scripting Definition (sdef) describes all the support, and you can open in in the Script Editor to see more details. Here are some examples of what you can do:

Just adding this until I can provide a more complete script.

The selection property will return whatever is selected, and has focus, in the Keyboard Maestro editor. So this could be any of these: action, macro, macro group. Here is how to get the selection, and determine the type (class) of the object that is selected:

snippet.applescript

tell application "Keyboard Maestro"
 
  --- First Select an Action, Macro, or Macro Group
  --    in the KM Editor, then run this script
 
  set kmList to selection
  set kmClass to class of item 1 of kmList
 
  -->Based on selection, will return one of these:
  -->action, macro, macro group
 
end tell

snippet.applescript

tell application "Keyboard Maestro"
  set selList to selection
  set macroList to selected macros
  set grpList to selected macro groups
end tell

snippet.applescript

tell application "Keyboard Maestro"
  #    Ver 1.1    2017-09-20
 
  set macroList to every macro whose selected is true
 
  --- Make Sure Only ONE Macro is Selected ---
 
  if ((count of macroList) = 1) then
    set oMacro to item 1 of macroList
  else
    error "Multiple Macros are selected.  Select only ONE and re-execute this script."
  end if
 
  --- Now We can Get/Set Macro Properties ---
 
  set macroName to name of oMacro
 
  return macroName
 
end tell

Disable a Macro Group

tell application "Keyboard Maestro"
   set enabled of macro group "Macro Group Name" to false
end tell

Edit a Macro Group

tell application "Keyboard Maestro"
  editMacro "Macro Group Name or UID"
end tell

Get the list of currently selected macro groups

tell application "Keyboard Maestro"
   set groupList to selected macro groups
end tell

[JMichaelTX: This script removed pending review & update].

Before you use a macro group you probably want to check if it exists. The following example tests for the macro group's existence, based on a Keyboard Maestro input variable containing the macro group name -macroGroup.

(This test is case-insensitive. For example macro group “Firefox” could also be specified as “firefox”.)

snippet.applescript

tell application "Keyboard Maestro Engine"
  set macroGroup to getvariable "macroGroup"
  if (macroGroup = "") then error "[ERROR]" & linefeed & "Invalid Macro Group Name. KM Variable \"" & "macroGroup" & "\" was empty or undefined."
end tell
 
tell application "Keyboard Maestro" -- Editor
  if exists macro group macroGroup then
    return true
  else
    return false
  end if
end tell

Here is a full example that creates a macro group called “Multiple Clipboards” and then creates 9 macros with hot Control-C and action to copy the clipboard to a named clipboard with name “Clipboard N” (where N is 1-9) and another set of 9 macros with hot key Control-V and action to paste from the named clipboard “Clipboard N”

snippet.applescript

tell application id "com.stairways.keyboardmaestro.editor"
	set mg to make new macro group with properties {name:"Multiple Clipboards"}
	tell mg
		repeat with i from 1 to 9
			set m to make new macro with properties {name:"Copy " & i}
			tell m
				make new trigger with properties {xml:"<dict>
						<key>FireType</key>
						<string>Pressed</string>
						<key>KeyCode</key>
						<integer>8</integer>
						<key>MacroTriggerType</key>
						<string>HotKey</string>
						<key>Modifiers</key>
						<integer>4096</integer>
					</dict>"}
				make new action with properties {xml:"<dict>
						<key>Action</key>
						<string>Copy</string>
						<key>MacroActionType</key>
						<string>ClipboardSwitcherMacroAction</string>
						<key>RedundandDisplayName</key>
						<string>Clipboard " & i & "</string>
					</dict>"}
			end tell
			set m to make new macro with properties {name:"Paste " & i}
			tell m
				make new trigger with properties {xml:"<dict>
						<key>FireType</key>
						<string>Pressed</string>
						<key>KeyCode</key>
						<integer>9</integer>
						<key>MacroTriggerType</key>
						<string>HotKey</string>
						<key>Modifiers</key>
						<integer>4096</integer>
					</dict>"}
				make new action with properties {xml:"<dict>
						<key>Action</key>
						<string>Paste</string>
						<key>MacroActionType</key>
						<string>ClipboardSwitcherMacroAction</string>
						<key>RedundandDisplayName</key>
						<string>Clipboard " & i & "</string>
					</dict>"}
			end tell
		end repeat
	end tell
end tell

You can get XML by creating sample macros and then using the Copy as XML in the Edit menu.